QPride MV2 is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose.
Used to control blood sugar levels
QPride MV2 is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor which prevents breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.
Voglibose target PPHG by reducing the intestinal absorption of carbohydrates after a meal thus redusing PPHG and HbA1c.
Metformin in an oral antidiabetic, Metformin decreases hepatic glucose production. Metformin also potentiates insulin action by decreasing insulin resistance.
COMPOSITION | Per serving (ml) |
---|---|
Glimepiride | 2mg |
Metformin | 500mgmg |
Voglibose | 0.2mg |
Glimepiride is the latest sulphonylurea. Glimepiride blocks potassium channels on the b cells of pancreas. This releases insulin. In addition it also has an extrapancreatic activity. Besides releasing insulin glimepiride by itself improves the sensitivity of the insulin receptor and thus improves the sensitivity of the insulin receptor and thus improves blood glucose control.
This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise.
Pregnant and lactating women should avoid using this tablet it may lead to fetal toxicity.
Alters potassium levels hence patients taking potassium supplements should intimate doctor before consuming the tablets.
One tablet once daily